Moonlight Sonata

Sumatriptan Side Effects

The frequency of adverse reactions below was determined according to the following: very often - more than 1/10; often from more than 1/100 to less than 1/10; sometimes from more than 1/1000 to less than 1/100; rarely - from more than 1/10 000 to less than 1/1000; very rarely - from less than 1/10 000, including individual cases.

From the nervous system: often - dizziness, drowsiness, impaired sensitivity, including parasthesia and decreased sensitivity.

On the part of the cardiovascular system: often - a transient increase in blood pressure (observed shortly after taking the drug), “hot flashes”.

From the respiratory system and organs, a group of cells: often - dyspnea, lung, transient irritation of the mucous membrane or burning sensation in the nasal cavity or throat, nosebleeds.

From the digestive tract: often - nausea, vomiting.

From the musculoskeletal system and connective tissue: often - a feeling of heaviness (usually transient, can be intense and occur in any part of the body, including the chest and throat).

General and local reactions: often - pain, a feeling of cold or heat, a feeling of pressure or constriction (usually transient, can be intense and occur in any part of the body, including the chest and throat), weakness, fatigue (usually mild or moderate, transient).

Laboratory indicators: very rarely - slight deviations in liver function tests.

From the immune system: very rarely - hypersensitivity reactions, including skin manifestations, as well as anaphylaxis.

From the nervous system: very rarely - convulsive seizures (in some cases observed in patients with a history of convulsive seizures or in concomitant conditions predisposing to seizures; in some patients, no risk factors were identified), tremor, dystonia, nystagmus, scotoma.

From the side of the organs of vision: very rarely - flickering, diplopia, decreased visual acuity, blindness (usually transient). Buy sumatriptan However, visual disturbances can be caused by a migraine attack itself..

From the cardiovascular system: very rarely - bradycardia, tachycardia, flutter, arrhythmias, transient ECG changes, coronary vasospasm, angina pectoris, myocardial infarction, hypotension, Raynaud's syndrome.

From the gastrointestinal tract: very rarely - ischemic colitis, dysphagia, a feeling of discomfort in the abdomen.

What are triptans, how do they affect a headache?

Triptans are drugs that help cope with migraines..

Means have the following effects:


  • the main effect is the effect on the vascular walls that provide cerebral blood supply - as a result, the vessels are narrowed, the person’s condition improves even with a prolonged attack of migraine;
  • high selectivity (selectivity) - the group acts only on the vessels of the brain, peripheral and coronary are excluded;
  • the trigeminal nerve becomes inflamed with migraine, and drugs act on its receptors, so the effectiveness of the drugs is high even with a severe form of pathology;
  • only triptans can eliminate additional signs of migraine - eye sensitivity to light, vomiting, nausea;
  • anti-inflammatory effect - swelling is reduced.


Pharmacological properties

Sumatriptan has two mechanisms of action when used:


  • excitation of serotonin 5-HT1 receptors of the muscles of the vessels of the carotid arteries, smooth muscle narrows under the action of the substance;
  • the drug blocks the production of sensory neuropeptides.


With the expansion of blood vessels, the brain receives a lot of blood, which leads to the formation of migraine. It does not have an analgesic effect, therefore, the use to eliminate other forms of headaches is not relevant.