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Cholestatic Jaundice/Hepatic Dysfunction

AUGMENTIN is contraindicated in patients with a previous history of cholestatic jaundice/hepatic dysfunction associated with AUGMENTIN.

Medications for Cellulitis: Augmentin, Cephalexin, Amoxicillin and Cipro

Cellulitis is a severe skin infection that can quickly turn to blood poisoning or gangrene. Without care, it can be life-threatening or require amputations. However, modern medicine for cellulitis can quickly tip the scales in most cases and you will be on your way to a full recovery.

Will Tonsillitis Go Away on Its Own?

Tonsils are the two oval-shaped pads of tissue in the back of your throat. buy augmentin online They help protect your body from infection. However, sometimes they get infected and inflamed (red and swollen) and this is called tonsillitis. Tonsillitis symptoms usually go away after three to four days.

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Side effects

When using the drug, the development of various undesirable effects is possible:

From the digestive system: loss of appetite, nausea, vomiting, abdominal pain, diarrhea, impaired liver function (increased activity of alkaline phosphatase and gamma-glutamyl transpeptidase), malabsorption syndrome (which manifests itself, including vitamin B12 deficiency).

From the nervous system: depression, peripheral neuritis, neuropathy.

From the hemopoietic organs: myelosuppression - leukopenia, agranulocytosis, neutropenia, aplastic anemia; with prolonged treatment - thrombocytopenia.

Allergic reactions: urticaria, measles-like rash.

Other: azoospermia, temporary alopecia, myopathy, impaired renal function.

With an overdose of the drug, nausea, vomiting, severe diarrhea, abdominal and oral pain, hemorrhagic gastroenteritis, burning of the skin, severe dehydration with a decrease in blood pressure (up to the development of hypovolemic shock), decrease in myocardial contractility, elevation of the ST segment on the ECG, hematuria develop , oliguria, convulsions, ascending paralysis, respiratory depression. Possible development of hepatocellular lesions, acute renal failure, pulmonary infiltrates.

5 days after an overdose, severe bone marrow depression may occur with leukopenia, thrombocytopenia, coagulopathy.

Treatment is carried out in a toxicological center. Buy colchicine There is no specific antidote. Hemodialysis is ineffective. It is necessary to control airway patency, assisted ventilation, monitoring and maintaining vital functions, normalizing the gas composition of the blood, electrolyte balance, and conducting anti-shock measures.

Drug properties

Calcium D3 Nycomed will help the body!

In the body of a person suffering from gout, a metabolic disorder occurs. As a result, there is an increased formation of uric acid, as well as the formation of salt crystals and their deposition on the surface of joints.

Salt crystals are called urates. They negatively affect the state of the human limbs, provoking a deformation of the appearance, as well as severe inflammatory processes. Exacerbation of gout occurs during the rest period..

After applying colchicine, the following processes occur in the human body:


  • The level of leukocyte migration to the inflamed area decreases;
  • In the area of ​​inflammation, the process of cell multiplication decreases;
  • The number of lysosomal enzymes that provoke a pathogenic reaction in the problem area is reduced;
  • The development of yeast-like bacteria is neutralized;
  • The process of producing acid that promotes the formation of gout is blocked;
  • Stops uric acid crystallization.


In addition to these properties, colchicine has the ability to anesthetize. Its use causes a general anti-inflammatory effect, preventing not only the elimination of the problem, but also prevention during periods of attenuation.

Composition and form of release

The medical tool "Colchicine" is implemented in the form of tablets consisting of colchicine, as the main component, and such auxiliary substances:


  • starch - a filler that provides dragees with a certain mass;
  • propyl paraben, methyl paraben - preservatives with antibacterial and antifungal properties;
  • milk sugar - a filler acting as a sweetener;
  • sodium starch glycolate - additives for the rapid dissolution of drug particles;
  • aerosil - thickener;
  • povidone - detoxifying effect.


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Sumatriptan Side Effects

The frequency of adverse reactions below was determined according to the following: very often - more than 1/10; often from more than 1/100 to less than 1/10; sometimes from more than 1/1000 to less than 1/100; rarely - from more than 1/10 000 to less than 1/1000; very rarely - from less than 1/10 000, including individual cases.

From the nervous system: often - dizziness, drowsiness, impaired sensitivity, including parasthesia and decreased sensitivity.

On the part of the cardiovascular system: often - a transient increase in blood pressure (observed shortly after taking the drug), “hot flashes”.

From the respiratory system and organs, a group of cells: often - dyspnea, lung, transient irritation of the mucous membrane or burning sensation in the nasal cavity or throat, nosebleeds.

From the digestive tract: often - nausea, vomiting.

From the musculoskeletal system and connective tissue: often - a feeling of heaviness (usually transient, can be intense and occur in any part of the body, including the chest and throat).

General and local reactions: often - pain, a feeling of cold or heat, a feeling of pressure or constriction (usually transient, can be intense and occur in any part of the body, including the chest and throat), weakness, fatigue (usually mild or moderate, transient).

Laboratory indicators: very rarely - slight deviations in liver function tests.

From the immune system: very rarely - hypersensitivity reactions, including skin manifestations, as well as anaphylaxis.

From the nervous system: very rarely - convulsive seizures (in some cases observed in patients with a history of convulsive seizures or in concomitant conditions predisposing to seizures; in some patients, no risk factors were identified), tremor, dystonia, nystagmus, scotoma.

From the side of the organs of vision: very rarely - flickering, diplopia, decreased visual acuity, blindness (usually transient). Buy sumatriptan However, visual disturbances can be caused by a migraine attack itself..

From the cardiovascular system: very rarely - bradycardia, tachycardia, flutter, arrhythmias, transient ECG changes, coronary vasospasm, angina pectoris, myocardial infarction, hypotension, Raynaud's syndrome.

From the gastrointestinal tract: very rarely - ischemic colitis, dysphagia, a feeling of discomfort in the abdomen.

What are triptans, how do they affect a headache?

Triptans are drugs that help cope with migraines..

Means have the following effects:


  • the main effect is the effect on the vascular walls that provide cerebral blood supply - as a result, the vessels are narrowed, the person’s condition improves even with a prolonged attack of migraine;
  • high selectivity (selectivity) - the group acts only on the vessels of the brain, peripheral and coronary are excluded;
  • the trigeminal nerve becomes inflamed with migraine, and drugs act on its receptors, so the effectiveness of the drugs is high even with a severe form of pathology;
  • only triptans can eliminate additional signs of migraine - eye sensitivity to light, vomiting, nausea;
  • anti-inflammatory effect - swelling is reduced.


Pharmacological properties

Sumatriptan has two mechanisms of action when used:


  • excitation of serotonin 5-HT1 receptors of the muscles of the vessels of the carotid arteries, smooth muscle narrows under the action of the substance;
  • the drug blocks the production of sensory neuropeptides.


With the expansion of blood vessels, the brain receives a lot of blood, which leads to the formation of migraine. It does not have an analgesic effect, therefore, the use to eliminate other forms of headaches is not relevant.